Bermuda Triangle: Mystery Solved

Mystery solved

Mutant mice lacking the integrin alpha8 subunit exhibit variable defects in kidney development with most mutants missing both kidneys. Several lines of evidence indicate that the known extracellular matrix ligands for integrin alpha8beta1 are either dispensable for or not involved in alpha8beta1 signaling during kidney development. This suggests the presence of an unknown ligand. A novel alpha8...

Pain: one mystery solved.

Surviving in the Bermuda Triangle of Semeiosis

What we think is part of reality and at least partly determined by reality at the same time. The advent of knowledge engineering asks for a shift from lifeless representational and blind reductionist models towards a relational and teleological interpretation of cognition in order to embed the cognitive events in processes of meaning production or semeiosis. Such embedding is determined by the ...

The magic angle: a solved mystery.

We resolve the long-standing mysterious discrepancy between the experimental magic angle in EELS--approximately 2theta(E)--and the quantum mechanical prediction of approximately 4theta(E). A relativistic approach surpassing the usually applied kinematic correction yields a magic angle close to the experimental value. The reason is that the relativistic correction of the inelastic scattering cro...

ACTH action on podocytes: mystery solved?

1 2 3 4 5 6 7 8 Editorial focus: 9 10 ACTH action on podocytes: mystery solved? 11 12 13 Paolo Cravedi and Kirk N Campbell 14 15 Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, New York 16 17 18 Running title: Melanocortins and podocytes 19 20 21 22 23 24 25 Word count: 947 26 27 28 29 30 31 32 33 34 35 Correspondence to: 36 Kirk N Campbell, MD 37 Division of Nephrolo...